Beanspruchtes

beanspruchtes material

claimed material

Statisch beanspruchtes Bauteil

Static stressed component

AUF KRAFTÜBERTRAGUNG BEANSPRUCHTES GETRIEBETEIL

DRIVING GEAR USED TO TRANSMIT POWER

Ein wie in Anspruch 1 beanspruchtes Verfahren zur Herstellung einer Verbindung, ausgewählt aus: 2-[5-(3-Benzyl-1,2,4-oxadiazol-5-yl)-1H-indol-3-yl]ethylamin, 2-[5-(3-Methyl-1,2,4-oxadiazol-5-yl)-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-(3-benzyl-1,2,4-oxadiazol-5-yl)-1H-indol-3-yl]ethylamin, 2-[5-(3-Benzyl-1,2,4-oxadiazol-5-ylmethyl)-1H-indol-3-yl]-ethylamin, 2-[5-(3-Methyl-1,2,4-oxadiazol-5-ylmethyl)-1H-indol-3-yl]-ethylamin, 2-[5-(3-Amino-1,2,4-oxadiazol-5-ylmethyl)-1H-indol-3-yl]ethylamin, 2-[5-(3-Phenyl-1,2,4-oxadiazol-5-ylmethyl)-1H-indol-3-yl]ethylamin, 2-[5-[3-(2-Methoxybenzyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-(3-benzyl-1,2,4-oxadiazol-5-ylmethyl)-1H-indol-3-yl]ethylamin, 2-[5-[2-(3-Benzyl-1,2,4-oxadiazol-5-yl)ethyl]-1H-indol-3-yl]-ethylamin, N,N-Dimethyl-2-[5-(3-methyl-1,2,4-oxadiazol-5-ylmethyl)-1H-indol-3-yl]ethylamin, 2-[5-(3-Diphenylmethyl-1,2,4-oxadiazol-5-yl)-1H-indol-3-yl]-ethylamin, 2-[5-(3-Phenyl-1,2,4-oxadiazol-5-yl)-1H-indol-3-yl]ethylamin, 2-[5-[3-(2-Methoxybenzyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]-ethylamin, 2-[5-[3-(3-Benzyl-1,2,4-oxadiazol-5-yl)propyl]-1H-indol-3-yl]ethylamin, 2-[5-(3-Phenethyl-1,2,4-oxadiazol-5-yl)-1H-indol-3-yl]ethylamin, 2-[5-(5-Benzyl-1,2,4-oxadiazol-3-yl)-1H-indol-3-yl]ethylamin, 2-[5-(5-Benzyl-1,2,4-oxadiazol-3-ylmethyl)-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-[3-(2-methoxybenzyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-[2-(3-benzyl-1,2,4-oxadiazol-5-yl)ethyl]-1H-indol-3-yl]ethylamin, 2-[5-[3-(1-Naphthyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamin, 2-[5-[3-(3-Methyl-1,2,4-oxadiazol-5-yl)propyl]-1H-indol-3-yl]-ethylamin, 2-[5-[3-(3-Cyclopropyl-1,2,4-oxadiazol-5-yl)propyl]-1H-indol-3-yl]ethylamin, 2-[5-[3-(3-Methoxybenzyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]-ethylamin, 2-[5-[3-(4-Methoxybenzyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]-ethylamin, 2-[5-[3-(4-Acetylaminobenzyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamin, 2-[5-[3-(4-Methylsulfonylaminobenzyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamin, 2-[5-[3-(3-Phenylpropyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]-ethylamin, 2-[5-(3-Cyclopropyl-1,2,4-oxadiazol-5-yl)-1H-indol-3-yl]ethylamin, 2-[5-(3-Ethyl-1,2,4-oxadiazol-5-yl)-1H-indol-3-yl]ethylamin, 2-[5-[3-(4-Trifluormethylbenzyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-[3-(4-acetylaminobenzyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-[3-(4-methylsulfonylaminobenzyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-(3-amino-1,2,4-oxadiazol-5-ylmethyl)-1H-indol-3-yl]ethylamin, 2-[5-[2-(3-Amino-1,2,4-oxadiazol-5-yl)ethyl]-1H-indol-3-yl]-ethylamin, 2-[5-[2-(3-Dimethylamino-1,2,4-oxadiazol-5-yl)ethyl]-1H-indol-3-yl]ethylamin, 2-[5-(5-Methyl-1,2,4-oxadiazol-3-yl)-1H-indol-3-yl]ethylamin, 2-[5-(5-Methyl-1,2,4-oxadiazol-3-ylmethyl)-1H-indol-3-yl]-ethylamin, N,N-Dimethyl-2-[5-(5-benzyl-1,2,4-oxadiazol-3-ylmethyl)-1H-indol-3-yl]ethylamin, 2-[5-(3-Methoxymethyl-1,2,4-oxadiazol-5-yl)-1H-indol-3-yl]-ethylamin, 2-[5-[3-(4-Methylaminocarbonylbenzyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamin, 2-[5-[3-(4-Methylaminocarbonylphenyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamin, 2-[5-[3-(4-Methylaminosulfonylbenzyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamin, 2-[5-[3-(4-Methylsulfonylbenzyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamin, 2-[5-[3-(3-Methylsulfonylaminobenzyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamin, 2-[5-[3-(4-Aminocarbonylaminobenzyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamin, 2-[5-(3-Amino-1,2,4-oxadiazol-5-yl)-1H-indol-3-yl]ethylamin, 2-[5-(3-Acetylaminomethyl-1,2,4-oxadiazol-5-yl)-1H-indol-3-yl]-ethylamin, 2-[5-[3-(2-Acetylaminoethyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamin, 2-[5-(3-Aminomethyl-1,2,4-oxadiazol-5-yl)-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-(3-amino-1,2,4-oxadiazol-5-yl)-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-(3-acetylaminomethyl-1,2,4-oxadiazol-5-yl)-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-[3-(2-acetylaminoethyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-[3-(4-aminocarbonylaminobenzyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-[3-(2-(t-butoxycarbonylamino)ethyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-[3-(4-methylaminocarbonylbenzyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-[3-(2-aminoethyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-[3-(2-methylsulfonylaminoethyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-[3-(2-aminocarbonylaminoethyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-[3-(2-methylaminocarbonylaminoethyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-[3-(2-methylaminocarbonylaminoethyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-[3-(2-methoxycarbonylaminoethyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-[3-(2-ethoxycarbonylaminoethyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-[2-(3-amino-1,2,4-oxadiazol-5-yl)ethyl]-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-(3-methylamino-1,2,4-oxadiazol-5-ylmethyl)-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-[3-(4-aminocarbonylbenzyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-[3-(4-acetylaminobenzyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-[3-(4-methylaminosulfonylbenzyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-[3-(4-aminocarbonylaminobenzyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-[3-(4-methylsulfonylaminobenzyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-[3-(4-methylaminocarbonylphenyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-(3-acetylaminomethyl-1,2,4-oxadiazol-5-yl-methyl)-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-(3-methylsulfonylaminomethyl-1,2,4-oxadiazol-5-ylmethyl)-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-(3-aminocarbonylmethyl-1,2,4-oxadiazol-5-yl-methyl)-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-[3-(3-methylsulfonylaminobenzyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-[3-(3-acetylaminobenzyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-[3-(4-aminocarbonylphenyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-[3-(3-aminocarbonylphenyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-[3-(4-methylsulfonylaminophenyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-[3-(4-methylaminosulfonylmethylphenyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-[3-(3-methylaminosulfonylmethylphenyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-[3-(4-aminosulfonylmethylphenyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-[3-(4-dimethylaminosulfonylmethylphenyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-[3-(t-butoxycarbonylamino)methyl-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-[3-(2-(t-butoxycarbonylamino)ethyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-(3-aminomethyl-1,2,4-oxadiazol-5-ylmethyl)-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-(3-methoxycarbonylaminomethyl-1,2,4-oxadiazol-5-ylmethyl)-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-(3-dimethylaminomethyl-1,2,4-oxadiazol-5-yl-methyl)-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-[3-(2-methylsulfonylaminoethyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-[3-(2-ethoxycarbonylaminoethyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-(3-benzoylaminomethyl-1,2,4-oxadiazol-5-yl-methyl)-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-[3-(2-benzoylaminoethyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-[3-(2-phenylaminocarbonylaminoethyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-[3-(2-(t-butylaminocarbonylamino)ethyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamin, N-Methyl-2-[5-(3-amino-1,2,4-oxadiazol-5-ylmethyl)-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-[3-(4-(t-butoxycarbonyl)piperazin-1-yl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-[3-(4-methylsulfonylpiperazin-1-yl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-[3-(4-methoxycarbonylpiperazin-1-yl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-[3-(4-methylaminocarbonylpiperazin-1-yl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-[3-(4-acetylpiperazin-1-yl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-[3-(4-methylsulfonylaminomethylphenyl)-1,2,4-oxadiazol-5-yl-methyl]-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-(3-phenylsulfonylaminomethyl-1,2,4-oxadiazol-5-ylmethyl)-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-(3-benzylamino-1,2,4-oxadiazol-5-ylmethyl)-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-[3-(3-pyridyl)methyl-1,2,4-oxadiazol-5-yl-methyl]-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-[3-(2-methoxypyrid-5-yl)methyl-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamin, 2-[5-[3-(4-Acetylaminobenzyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamin, 2-[5-[3-(4-Methylsulfonylaminobenzyl)-1,2,4-oxadiazol-5-yl-methyl]-1H-indol-3-yl]ethylamin, 2-[5-[2-[3-(4-Acetylaminobenzyl)-1,2,4-oxadiazol-5-yl]ethyl]-1H-indol-3-yl]ethylamin, 2-[5-[2-[3-(4-Methoxybenzyl)-1,2,4-oxadiazol-5-yl]ethyl]-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-(5-methyl-1,3-oxazol-2-yl)-1H-indol-3-yl]-ethylamin, N,N-Dimethyl-2-[5-[2-(5-methyl-1,3-oxazol-2-yl)ethyl]-1H-indol-3-yl]ethylamin, 1-Methyl-4-[5-(3-amino-1,2,4-oxadiazol-5-yl)-1H-indol-3-yl]-piperidin, 1-Methyl-4-[5-(3-amino-1,2,4-oxadiazol-5-ylmethyl)-1H-indol-3-yl]piperidin, 1-Methyl-4-[5-[3-(4-methylsulfonylaminobenzyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]piperidin, 1-Methyl-4-[5-[3-(3-pyridyl)methyl-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]piperidin, N,N-Dimethyl-2-[5-[3-(4-pyridyl)methyl-1,2,4-oxadiazol-5-yl-methyl]-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-[3-(2-(t-butoxycarbonylamino)ethyl)amino-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamin, 2-[5-(3-Aminocarbonyl-1,2,4-oxadiazol-5-ylmethyl)-1H-indol-3-yl]ethylamin, 2-[5-(3-Methylaminocarbonyl-1,2,4-oxadiazol-5-ylmethyl)-1H-indol-3-yl]ethylamin, 2-[5-[3-(Pyrrolid-1-yl)carbonyl-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamin, 2-[5-[3-(Azetidin-1-yl)carbonyl-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-[3-(4-phenylsulfonylpiperazin-1-yl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-[3-(2-(pyrrolid-1-ylcarbonylamino)ethyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-[3-(2-methylsulfonylaminoethyl)amino-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamin, N,N-Dimethyl-2-[5-(3-amino-1,4-thiadiazol-5-ylmethyl)-1H-indol-3-yl]ethylamin und von Salzen davon.

A process as claimed in Claim 1 for the preparation of a compound selected from: 2-[5-(3-benzyl-1,2,4-oxadiazol-5-yl)-1H-indol-3-yl]ethylamine; 2-[5-(3-methyl-1,2,4-oxadiazol-5-yl)-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-(3-benzyl-1,2,4-oxadiazol-5-yl)-1H-indol-3-yl]ethylamine; 2-[5-(3-benzyl-1,2,4-oxadiazol-5-ylmethyl)-1H-indol-3-yl]ethylamine; 2-[5-(3-methyl-1,2,4-oxadiazol-5-ylmethyl)-1H-indol-3-yl]ethylamine; 2-[5-(3-amino-1,2,4-oxadiazol-5-ylmethyl)-1H-indol-3-yl]ethylamine; 2-[5-(3-phenyl-1,2,4-oxadiazol-5-ylmethyl)-1H-indol-3-yl]ethylamine; 2-[5-[3-(2-methoxybenzyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-(3-benzyl-1,2,4-oxadiazol-5-ylmethyl)-1H-indol-3-yl]ethylamine; 2-[5-[2-(3-benzyl-1,2,4-oxadiazol-5-yl)ethyl]-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-(3-methyl-1,2,4-oxadiazol-5-ylmethyl)-1H-indol-3-yl]ethylamine; 2-[5-(3-diphenylmethyl-1,2,4-oxadiazol-5-yl)-1H-indol-3-yl]ethylamine; 2-[5-(3-phenyl-1,2,4-oxadiazol-5-yl)-1H-indol-3-yl]ethylamine; 2-[5-[3-(2-methoxybenzyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamine; 2-[5-[3-(3-benzyl-1,2,4-oxadiazol-5-yl)propyl]-1H-indol-3-yl]ethylamine; 2-[5-(3-phenethyl-1,2,4-oxadiazol-5-yl)-1H-indol-3-yl]ethylamine; 2-[5-(5-benzyl-1,2,4-oxadiazol-3-yl)-1H-indol-3-yl]ethylamine; 2-[5-(5-benzyl-1,2,4-oxadiazol-3-ylmethyl)-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-[3-(2-methoxybenzyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-[2-(3-benzyl-1,2,4-oxadiazol-5-yl)ethyl]-1H-indol-3-yl]ethylamine; 2-[5-[3-(1-naphthyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamine; 2-[5-[3-(3-methyl-1,2,4-oxadiazol-5-yl)propyl]-1H-indol-3-yl]ethylamine; 2-[5-[3-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)propyl]-1H-indol-3-yl]ethylamine; 2-[5-[3-(3-methoxybenzyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamine; 2-[5-[3-(4-methoxybenzyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamine; 2-[5-[3-(4-acetylaminobenzyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamine; 2-[5-[3-(4-methylsulphonylaminobenzyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamine; 2-[5-[3-(3-phenylpropyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamine; 2-[5-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)-1H-indol-3-yl]ethylamine; 2-[5-(3-ethyl-1,2,4-oxadiazol-5-yl)-1H-indol-3-yl]ethylamine; 2-[5-[3-(4-trifluoromethylbenzyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-[3-(4-acetylaminobenzyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-[3-(4-methylsulphonylaminobenzyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-(3-amino-1,2,4-oxadiazol-5-ylmethyl)-1H-indol-3-yl]ethylamine; 2-[5-[2-(3-amino-1,2,4-oxadiazol-5-yl)ethyl]-1H-indol-3-yl]ethylamine; 2-[5-[2-(3-dimethylamino-1,2,4-oxadiazol-5-yl)ethyl]-1H-indol-3-yl]ethylamine; 2-[5-(5-methyl-1,2,4-oxadiazol-3-yl)-1H-indol-3-yl]ethylamine; 2-[5-(5-methyl-1,2,4-oxadiazol-3-ylmethyl)-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-(5-benzyl-1,2,4-oxadiazol-3-ylmethyl)-1H-indol-3-yl]ethylamine; 2-[5-(3-methoxymethyl-1,2,4-oxadiazol-5-yl)-1H-indol-3-yl]ethylamine; 2-[5-[3-(4-methylaminocarbonylbenzyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamine; 2-[5-[3-(4-methylaminocarbonylphenyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamine; 2-[5-[3-(4-methylaminosulphonylbenzyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamine; 2-[5-[3-(4-methylsulphonylbenzyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamine; 2-[5-[3-(3-methylsulphonylaminobenzyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamine; 2-[5-[3-(4-aminocarbonylaminobenzyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamine; 2-[5-(3-amino-1,2,4-oxadiazol-5-yl)-1H-indol-3-yl]ethylamine; 2-[5-(3-acetylaminomethyl-1,2,4-oxadiazol-5-yl)-1H-indol-3-yl]ethylamine; 2-[5-[3-(2-acetylaminoethyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamine; 2-[5-(3-aminomethyl-1,2,4-oxadiazol-5-yl)-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-(3-amino-1,2,4-oxadiazol-5-yl)-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-(3-acetylaminomethyl-1,2,4-oxadiazol-5-yl)-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-[3-(2-acetylaminoethyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-[3-(4-aminocarbonylaminobenzyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-[3-(2-(t-butoxycarbonylamino)ethyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-[3-(4-methylaminocarbonylbenzyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-[3-(2-aminoethyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-[3-(2-methylsulphonylaminoethyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-[3-(2-aminocarbonylaminoethyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-[3-(2-methylaminocarbonylaminoethyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-[3-(2-methylaminocarbonylaminoethyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-[3-(2-methoxycarbonylaminoethyl)-1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-[3-(2-ethoxycarbonylaminoethyl)1,2,4-oxadiazol-5-yl]-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-[2-(3-amino-1,2,4-oxadiazol-5-yl)ethyl]-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-(3-methylamino-1,2,4-oxadiazol-5-ylmethyl)-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-[3-(4-aminocarbonylbenzyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-[3-(4-acetylaminobenzyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-[3-(4-methylaminosulphonylbenzyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-[3-(4-aminocarbonylaminobenzyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-[3-(4-methylsulphonylaminobenzyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-[3-(4-methylaminocarbonylphenyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-(3-acetylaminomethyl-1,2,4-oxadiazol-5-ylmethyl)-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-(3-methylsulphonylaminomethyl-1,2,4-oxadiazol-5-ylmethyl)-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-(3-aminocarbonylmethyl-1,2,4-oxadiazol-5-ylmethyl)-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-[3-(3-methylsulphonylaminobenzyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-[3-(3-acetylaminobenzyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-[3-(4-aminocarbonylphenyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-[3-(3-aminocarbonylphenyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-[3-(4-methylsulphonylaminophenyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-[3-(4-methylaminosulphonylmethylphenyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-[3-(3-methylaminosulphonylmethylphenyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-[3-(4-aminosulphonylmethylphenyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-[3-(4-dimethylaminosulphonylmethylphenyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-[3-(t-butoxycarbonylamino)methyl-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-[3-(2-(t-butoxycarbonylamino)ethyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-(3-aminomethyl-1,2,4-oxadiazol-5-ylmethyl)-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-(3-methoxycarbonylaminomethyl-1,2,4-oxadiazol-5-ylmethyl)-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-(3-dimethylaminomethyl-1,2,4-oxadiazol-5-ylmethyl)-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-[3-(2-methylsulphonylaminoethyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-[3-(2-ethoxycarbonylaminoethyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-(3-benzoylaminomethyl-5-ylmethyl)-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-[3-(2-benzoylaminoethyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-[3-(2-phenylaminocarbonylaminoethyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-[3-(2-(t-butylaminocarbonylamino)ethyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamine; N-methyl-2-[5-(3-amino-1,2,4-oxadiazol-5-ylmethyl)-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-[3-(4-(t-butoxycarbonyl)piperazin-1-yl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-[3-(4-methylsulphonylpiperazin-1-yl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-[3-(4-methoxycarbonylpiperazin-1-yl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-[3-(4-methylaminocarbonylpiperazin-1-yl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-[3-(4-acetylpiperazin-1-yl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-[3-(4-methylsulphonylaminomethylphenyl)-1,2,4-oxadiazol-5-yl-methyl]-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-(3-phenylsulphonylaminomethyl-1,2,4-oxadiazol-5-ylmethyl)-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-(3-benzylamino-1,2,4-oxadiazol-5-ylmethyl)-1H-indol-3-yl]ethylamine;. N,N-dimethyl-2-[5-[3-(3-pyridyl)methyl-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-[3-(2-methoxypyrid-5-yl)methyl-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamine; 2-[5-[3-(4-acetylaminobenzyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamine; 2-[5-[3-(4-methylsulphonylaminobenzyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamine; 2-[5-[2-[3-(4-acetylaminobenzyl)-1,2,4-oxadiazol-5-yl]ethyl]-1H-indol-3-yl]ethylamine; 2-[5-[2-[3-(4-methoxybenzyl)-1,2,4-oxadiazol-5-yl]ethyl]-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-(5-methyl-1,3-oxazol-2-yl)-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-[2-(5-methyl-1,3-oxazol-2-yl)ethyl]-1H-indol-3-yl]ethylamine; 1-methyl-4-[5-(3-amino-1,2,4-oxadiazol-5-yl)-1H-indol-3-yl]piperidine; 1-methyl-4-[5-(3-amino-1,2,4-oxadiazol-5-ylmethyl)-1H-indol-3-yl]piperidine; 1-methyl-4-[5-[3-(4-methylsulphonylaminobenzyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]piperidine; 1-methyl-4-[5-[3-(3-pyridyl)methyl-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]piperidine; N,N-dimethyl-2-[5-[3-(4-pyridyl)methyl-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-[3-(2-(t-butoxycarbonylamino)ethyl)amino-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamine; 2-[5-(3-aminocarbonyl-1,2,4-oxadiazol-5-ylmethyl)-1H-indol-3-yl]ethylamine; 2-[5-(3-methylaminocarbonyl-1,2,4-oxadiazol-5-ylmethyl)-1H-indol-3-yl]ethylamine; 2-[5-[3-(pyrrolid-1-yl)carbonyl-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamine; 2-[5-[3-(azetidin-1-yl)carbonyl-1,2,4-oxadiazol-5-ylmethyl]1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-[3-(4-phenylsulphonylpiperazin-1-yl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-[3-(2-(pyrrolid-1-ylcarbonylamino)ethyl)-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-[3-(2-methylsulphonylaminoethyl)amino-1,2,4-oxadiazol-5-ylmethyl]-1H-indol-3-yl]ethylamine; N,N-dimethyl-2-[5-(3-amino-1,4-thiadiazol-5-ylmethyl)-1H-indol-3-yl]ethylamine; and salts thereof.