ubiquitär

ubiquitär

ubiquitous

ubiquitär

ubiquist

Darmgeräusche spärlich aber ubiquitär vorhanden.

Bowel sounds are sparse but ubiquitously present.

Glycosaminoglycane bilden zusammen mit den Bindegewebeproteinen die ubiquitär vorkommenden Proteoglycane.

Glycosaminoglycans together with connecting tissue proteins form the ubiquitously present proteoglycans.

*ATP6V0B*ATP6V0C*ATP6V1E*ATP6V1F*ATP6V1G1==== Lysosom ====*CTSD, baut in Hepatozyten Insulin ab*Cystatin B, schützt vermutlich die Zelle vor undichten Lysosomen*LAMP1*Mannose-6-phosphat-Rezeptor*SGSH, Mutationen können das Sanfilippo-Syndrom erzeugen==== Proteasom ====*PSMB1*PSMB2*PSMB4*PSMB6*PSMA7*PSMB7*PSMD8*PSMD11*PSME2*UBA1*Ubiquitin B*UBE2I*UBE2D2*UBE2M*USP11==== Ribonuklease ====*RNH Ribonuklease-Hemmstoff==== Oxidase/Reduktase ====*TXN Thioreduktase=== Strukturelle Proteine ======= Zytoskelett ====*Actinin alpha 4*ACTG1 gamma-Aktin*ADD1*ANXA6*ARPC4 "Actin-related protein 2/3 complex"*Beta-Aktin*CAPZB*COL6A1*DNCL1 Cytoplasmic Dynein*EZR Ezrin (verankert Aktin in der Zellmembran)*KIFC3 kinesin*Moesin*MYH9 "Myosin, heavy chain 9"*RHOA vermutlich am Zellzyklus beteiligt*SEPT1 homolog zu CDC10 in "S. cerevesiae"*SEPT2*SLC9A3R2 bindet SLC9A3 an das Zytoskelett*TAGLN*TAGLN2*TMSB10 Thymosin ?10*TUBB Tubulin, beta-Polypeptid*TUBB4*WDR1==== Organellsynthese ====Eine spezielle Form der Zellsignalisierung*BLOC1S1*AP2M1*ANXA2*ANXA6*ANXA7*AP1B1 Endozytose*CLTA Clathrin A (Vesikel)*CLTB Clathrin B (Vesikel)*GP2 enzymatische sekretorische Granula (v. a. im Pankreas)*KDELR1 KDEL-Rezeptor bindet ER-Proteine==== Mitochondrium ====*MTX1=== Zelloberfläche ===*AP2S1*CD81*GPAA1*LGALS9*MGAT1*VAMP3==== Zelladhäsion ====*ADAM15*Beta-catenin*CNTN1 Contactin*Delta-catenin==== Kanäle und Transporter ====*ABCG2 früher BCRP1 xenobiotic transporter, gering exprimiert*CALM1 Calmodulin bindet Calciumionen*CALM2 Calmodulin bindet Calciumionen*HPCAL1 bindet Calciumionen; exprimiert v. a. in der Retina*GRIK5*MFSD10 aka TETRAN or tetracycline transporter-like protein*TFRC Transferrinrezeptor*FOLR1 Folatrezeptor*SLC25A11 mitochondrialer Oxoglutarat/Malat-Transporter==== Rezeptoren ====*ACVRL1 TGF-?-Rezeptorfamilie (Morbus Osler)*CD23A FCER2 low affinity IgE receptor (Lectin)*GRM4 metabotoper Glutamatrezeptor*JAG1 NOTCH2-Rezeptor "assoziiert mit dem Alagille-Syndrom"*MC2R Melanocortin-2-Rezeptor (ähnlich dem ACTH-Rezeptor)*SSTR5 Somatostatin-Rezeptor; neigt dazu, andere Hormone hemmen==== HLA, Immunoglobuline und Zellerkennung ====*BAT1*BSG Basigin-Immunglobulin-Superfamilie, extrazelluläre Metalloproteinase*B2M ?2-Mikroglobulin*HLA-C*HLA-G*MIF Macrophagenmigration inhibierender Faktor*TAPBP=== Kinasen und Signaltransduktion ===*ADRBK1 mindert die Reaktion auf Epinephrin*AGPAT1 3-Phosphoglycerol-Acyltransferase*ARF1*ARF3*ARF4*ARF5*ARL2 RAS-Superfamilie*CSF1 Koloniestimulierender Faktor, gering exprimiert*CSK C-src tyrosine kinase*DCT Dopachrom-Tautomerase*EFNA3*FKBP1A*GDI1 GDI-Dissoziationsinhibitor (Rab-Familie)*GNAS1 ubiquitär exprimiert, aber differentielles Imprinting*GNAI2*HAX1 assoziiert mit Tyrosinkinasen*ILK Integrin linked kinase*MAPKAPK2*MAP2K2*MAP3K11*PITPNM Phosphatidylinositol-Transfer-Proteine*RAC1 Rho-GTPase*RAP1B GTPase, beteiligt an der Zelladhäsion*RAGA Ras-verwandtes GTP-bindendes Protein*STK19*STK24 Serin/Threonin-Kinase*STK25*YWHAB Tyrosin-3-Monooxygenase/Tryptophan-5-Monooxygenase aktivierendes Protein, ?-Polypeptid*YWHAH Tyrosin-3-Monooxygenase/Tryptophan-5-Monooxygenase aktivierendes Protein, h-Polypeptid*YWHAQ Tyrosin-3-Monooxygenase/Tryptophan-5-Monooxygenase aktivierendes Protein, ?-Polypeptid*YWHAZ Tyrosin-3-Monooxygenase/Tryptophan-5-Monooxygenase aktivierendes Protein, ?-Polypeptid==== Wachstumsfaktoren ====*AIF1*HDGF Hepatom-abgeleiteter Wachstumsfaktor (transloziert zum Zellkern)*HGS*LTBP4*VEGFB*ZFP36L1==== Gewebe-Nekrose-Faktoren ====*CD40 früher TNFRSF5==== Caseinkinasen ====*CSNK1E*CSNK2B=== Verschiedenes ===*ALAS1 ?-Aminolävulinatsynthase Typ 1 (Typ 2 ist erythroid und mit Porphyrie assoziiert)*ARHGEF2 Guanin-Nukleotid-Austauschfaktor*ARMET Mesencephalere Astrozyten-abgeleiteter neurotropher Faktor*AES Amino-terminal Enhancer of Split*BECN1 beteiligt an der Autophagie*BUD31 früher Maternal G10 transcript*Creatine kinase CKB (ATP-Reservoir)*Cytidine deaminase*CPNE1*ENSA (gene)*FTH1 Ferritin schwere Kette*GDI2 rab/ras vesikulärer Transport*GUK1 Guanylatkinase*HPRT Hypoxanthine-guanine phosphoribosyltransferase*IFITM1 "Induced by interferon, transmembrane protein"*JTB (gene) Jumping translocation breakpoint*MMPL2*NME2 (früher NM23B) Nukleosid-Diphosphat-Kinase*NONO*P4HB*PRDX1 Peroxiredoxin (reduziert Peroxide)*PTMA Prothymosin*RPA2 Bindet DNA während der Replikation und streckt sie*SULT1A3 Sulfotransferase*SYNGR2 Synaptogyrin (nimmt möglicherweise an der Vesikeltranslokation teil)*Tetratricopeptide, TTC1 "small glutamine rich tetratricopeptide"==== Offene Leseraster ====*C11Orf13*C14orf2*C21orf33==== Begrenzt auf Spermien oder Hoden ====*SPAG7*SRM Spermidinsynthase*TEGT Bax-Inhibitor 1*DAZAP2 Gendeletion im Fall von Azoospermie*MEA1 Male Enhanced Antigen 1== Einzelnachweise ==

====Organelle Synthesis===="A specialized form of cell signaling"*BLOC1S1*BLOC1S2NM_173809*BLOC1S3NM_212550*BLOC1S4NM_018366*BLOC1S6NM_012388*AP1G1 NM_001128*AP1M1 NM_032493*AP2A1 NM_014203*AP2A2 NM_012305*AP2M1*AP2S1 NM_004069*AP3B1 NM_003664*AP3D1 NM_003938*AP3M1 NM_012095*AP3S1 NM_001284*AP3S2 NM_005829*AP4B1 NM_006594*AP5M1 NM_018229*ANXA6 Annexin 6*ANXA7 Annexin 7*AP1B1 Coated vessicles*CLTA Clathrin A (vessicles)*CLTB Clathrin B (vessicles)*CLTC====Mitochondrion====*MTX2===Surface===*AP2S1*CD81*GPAA1*LGALS9*MGAT2*MGAT4B*VAMP3====Cell Adhesion====*CTNNA1 NM_001903*CTNNB1*CTNNBIP1 NM_020248*CTNNBL1 NM_030877*CTNND1 NM_001085458 delta catenin====Channels and Transporters====*ABCB10 NM_012089*ABCB7 NM_004299*ABCD3 NM_002857*ABCE1 NM_002939*ABCF1 NM_001090*ABCF2 NM_005692*ABCF3 NM_018358*CALM1 Calmodulin grasps calcium ions*MFSD11 NM_024311 similar to MSFD10 aka TETRAN or tetracycline transporter-like protein*MFSD12 NM_174983*MFSD3 NM_138431*MFSD5 NM_032889*SLC15A4 NM_145648*SLC20A1 NM_005415*SLC25A11 mitochondrial oxoglutarate/malate carrier*SLC25A26 NM_173471*SLC25A28 NM_031212*SLC25A3 NM_002635*SLC25A32 NM_030780*SLC25A38 NM_017875*SLC25A39 NM_016016*SLC25A44 NM_014655*SLC25A46 NM_138773*SLC25A5 NM_001152*SLC27A4 NM_005094*SLC30A1 NM_021194*SLC30A5 NM_022902*SLC30A9 NM_006345*SLC35A2 NM_005660*SLC35A4 NM_080670*SLC35B1 NM_005827*SLC35B2 NM_178148*SLC35C2 NM_015945*SLC35E1 NM_024881*SLC35E3 NM_018656*SLC35F5 NM_025181*SLC38A2 NM_018976*SLC39A1 NM_014437*SLC39A3 NM_144564*SLC39A7 NM_006979*SLC41A3 NM_017836*SLC46A3 NM_181785*SLC48A1 NM_017842====Receptors====*ACVR1 NM_001105 similar to ACVRL1 TGF Beta receptor family "Rendu-Osler-Weber syndrome"*ACVR1B NM_004302*CD23 FCER2 low affinity IgE receptor (lectin)====HLA/Immunoglobulin/Cell recognition====*BAT1 aka DDX39B which is involved in RNA splicing*BSG Basigin Immunoglobulin Superfamily, extracelluar metalloproteinase*MIF macrophage migration inhibitory factor*TAPBP===Kinases/Signalling===*ADRBK1 can downregulate response to epinephrine*AGPAT1 acyl 3 phosphoglycerol acyl transferase*ARF1*ARF3*ARF4*ARF5*ARL2 RAS Superfamily*CSF1 Colony stimulating factor "not highly expressed constitutively at 5-12"*CSK C-src tyrosine kinase*DCT dopachrome tautomerase*EFNA3*FKBP1A*GDI1 GDP Dissociation inhibitor (Rab family)*GNAS1 ubiquitously expressed, but differentially imprinted*GNAI2*HAX1 associated with tyrosine kinases*ILK Integrin linked kinase*MAPKAPK2*MAP2K2*MAP3K11*PITPNM Phosphatidylinositol transfer protein*RAC1 Ro GTPase involved with many signaling pathways*RAP1B GTPase involved with cell adhesion*RAGA Ras-related GTP Binding*STK19*STK24 Serine/Threonine Kinase*STK25*YWHAB Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide*YWHAH Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, h polypeptide*YWHAQ Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide*YWHAZ Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide====Growth Factors====*AIF1*HDGF Hepatoma derived growth factor "(translocates to nucleus)"*HGS*LTBP4*VEGFB*ZFP36L1====Tissue Necrosis Factor====*CD40 formerly TNFRSF5====Casein Kinase====*CSNK1E*CSNK2B===Miscellaneous===*ALAS1 Aminolevulinic Acid Synthase type 1 (type 2 is erythroid and associated with porphyria)*ARHGEF2 Rho guanine nucleotide exchange factor*ARMET Mesencephalic astrocyte-derived neurotrophic factor*AES amino terminal enhancer of split*BECN1 involved in autophagy and partners with PI3K*BUD31 formerly Maternal G10 transcript*Creatine kinase CKB (ATP reservoir)*Cytidine deaminase "questionable: not present in very high levels at all"*CPNE1*ENSA (gene)*FTH1 Heavy chain of Ferritin*GDI2 rab/ras vessicular trafficking*GUK1 Guanylate kinase transfers phosphate from ATP to GMP*HPRT Hypoxanthine-guanine phosphoribosyltransferase*IFITM1 "Induced by interferon, transmembrane protein"*JTB (gene) Jumping translocation breakpoint*MMPL2*NME2 (formerly NM23B) Nucleoside diphosphate kinase*NONO*P4HB*PRDX1 peroxiredoxin (reduces peroxides)*PTMA Prothymosin*RPA2 Binds DNA during replication to keep it straightened out*SULT1A3 Sulfate conjugation "(note: SULT1C is cited in earlier literature as being ubiquitous but this may be an example of different tags being used to refer to a common area of 2 closely related genes.

Spuren ubiquitär vorhanden

Tracks available ubiquitously

ubiquitär

ubiquitously

Das Maul-und-Klauenseuche-Virus ist im Grunde genommen in Westeuropa mittlerweile exotisch, und das Blauzungenvirus, dessen Status sich zwar in jüngster Zeit verändert hat, ist in den meisten Ländern der EU nicht ubiquitär oder endemisch, weshalb die praktischen Risiken für diese beiden Krankheitserreger geringer sein dürften.

Foot and Mouth virus is virtually exotic to Western Europe and Bluetongue, although of a recent change in status, is not ubiquitous or endemic in the majority of the EU, so for these 2 agents the practical risks should be lower.