necrolysis

Lichenoid keratosis, lichen planus Toxic epidermal necrolysis Musculoskeletal and connective tissue disorders

Lichenoide Keratose, Lichen planus Toxische epidermale Nekrolyse Skelettmuskulatur-, Bindegewebs-und Knochenerkrankungen

Lichenoid keratosis, lichen planus Toxic epidermal necrolysis

Lichenoide Keratose, Lichen planus Toxische epidermale Nekrolyse

diaphoresis, pemphigus, toxic epidermal necrolysis, Stevens-Johnson Syndrome, erythema multiforme.

Diaphorese, Pemphigus, toxische epidermale Nekrolyse, Stevens-Johnson-

Isolated cases of Stevens-Johnson syndrome or Stevens-Johnson/toxic epidermal necrolysis transition syndrome have been reported in this population.

Einzelfälle von Stevens-Johnson-Syndrom oder Übergangssyndrom vom Stevens-Johnson-Syndrom zu toxisch epidermaler Nekrolyse sind bei diesem Kollektiv beobachtet worden.

Stevens-Johnson syndrome, epidermal necrolysis, erythema multiforme, urticaria, onycholysis (patients on therapy should wear sun protection on hands and feet)

Obstruktion/Perforation des Darms, pseudomembranöse Kolitis, ischämische Kolitis, mesenterische Thrombose, nekrotisierende Enterokolitis, Ösophagitis, Ascites, akute Pankreatitis

Stevens Johnson syndrome, toxic epidermal necrolysis,

Stevens-Johnson-Syndrom, toxische epidermale Nekrolyse,

Toxic epidermal necrolysis,

Leberversagen, Cholangitis, Fettleber

Common: abdominal pain, dyspepsia, constipation, diarrhoea, Gastrointestinal flatulence, oesophageal ulcer*, dysphagia*, abdominal distension, disorders: acid regurgitation Uncommon: nausea, vomiting, gastritis, oesophagitis*, oesophageal erosions*, melena Rare: oesophageal stricture*, oropharyngeal ulceration*, upper gastrointestinal PUBs (perforation, ulcers, bleeding)(see section 4.4) . *See sections 4.2 and 4.4 Uncommon: rash, pruritus, erythema Skin and rare: rash with photosensitivity subcutaneous tissue Very rare: severe skin reactions including Stevens-Johnson syndrome disorders: and toxic epidermal necrolysis Common: musculoskeletal (bone, muscle or joint) pain Musculoskeletal and Rare: severe musculoskeletal (bone, muscle or joint) pain (see connective tissue section 4.4) disorders:

Common: abdominal pain, dyspepsia, constipation, diarrhoea, Gastrointestinal flatulence, oesophageal ulcer*, dysphagia*, abdominal distension, disorders: acid regurgitation Uncommon: nausea, vomiting, gastritis, oesophagitis*,oesophageal erosions*, melena Rare: oesophageal stricture*, oropharyngeal ulceration*, upper gastrointestinal PUBs (perforation, ulcers, bleeding)(see section 4.4). *See sections 4.2 and 4.4 Uncommon: rash, pruritus, erythema Skin and rare: rash with photosensitivity subcutaneous tissue Very rare: severe skin reactions including Stevens-Johnson syndrome disorders: and toxic epidermal necrolysis Common: musculoskeletal (bone, muscle or joint) pain Musculoskeletal and Rare: severe musculoskeletal (bone, muscle or joint) pain (see connective tissue section 4.4) disorders: