Dioxid

zuviel kohlenstoff dioxid kann zur einer Erderwärmung führen

too much carbon dioxide can lead to a global warming

was du tun kannst um kohlenstoff dioxid zu verringern

what you can do to reduce carbon dioxide

DIOXID

Dioxides

kohlen dioxid

coal dioxide

HERSTELLUNG VON LITHIUM NICKEL KOBALT DIOXID

SYNTHESIS OF LITHIUM NICKEL COBALT DIOXIDE

Herbizide Mischung, enthaltend a) mindestens einen Cyclohexenonoximether der Formel I in der die Variablen folgende Bedeutungen haben: und b) mindestens eine der folgenden 44 herbiziden Verbindungen aus den Gruppen b1 bis b20) Herbizide Mischung nach Anspruch 1, enthaltend als Komponente b) mindestens eines der folgenden 33 Herbizide: b1) 2-Brom-3,3-dimethyl-N-(1-methyl-1-phenylethyl)-butyramid (Common name: bromobutide), S-(1-Methyl-1-phenylethyl)-1-piperidincarbothioat (Common name: Dimepiperate), 4-Ethoxybenz-2',3'-dihydrochloranilid (Common name: Etobenzanid), N-(3,4-dichlorophenyl)-propanamid (Common name: Propanil); b2) 2-(1,3-Benzthiazol-2-yloxy)-N-methyl-acetanilid (Common name: Mefenacet); b3) (2,4-Dichlorphenoxy)essigsäure (Common name: 2,4-D), 4-(4-Chlor-2-methylphenoxy)-butancarbonsäure (Common name: MCPB), 2-(2-Naphthyloxy)-propionanilid (Common name: Naproanilide); b4) 3-Isopropyl-1H-2,1,3-benzothiadiazin-4-(3H)one-2,2-dioxid (Common name: Bentazon); b5) 4-(2,4-Dichlorbenzoyl)-1,3-dimethyl-pyrazol-5-yl-toluyl-4-sulfonat (Common name: Pyrazolynate, Pyrazolate), 2-(2-Chlor-4-mesylbenzoyl)-cyclohexan-1,3-dion (Common name: Sulcotrione), b6) S-Benzyl-1,2-dimethylpropyl(ethyl)-thiocarbamat (Common name: Esprocarb), N-(Ethylthio-carbonyl)-azepan (Common name: Molinace), N,N-Diethyl-carbaminsäure-4-chlorbenzylthioester (Common name: Thiobencarb), b7) 3,7-Dichlorchinolin-8-carbonsäure (Common name: Quinclorac); b8) N-(Butoxymethyl)-2-chlor-N-(2,6-diethylphenyl)-acetamid (Common name: Butachlor), (Z)-N-But-2-enyloxymethyl-2-chlor-2',6'-diethylacetanilid (Common name: Butenachlor), N-(2-Propoxyethyl)-2-chlor-N-(2,6-diethylphenyl)acetamid (Common name: Pretilachlor), ?-Chlor-N-(3-methoxy-2-thienyl)-methyl-2',6'-dimethylacetanilid (Common name: Thenylchlor); b11) 2-[4-(6-Chlorbenzoxazol-2-yloxy)-phenoxy]-propionsäureethylester (Common name: Fenoxapropethyl); b12) 2-[4-(2,4-Dichlor-m-toluyl)-1,3-dimethylpyrazol-5-yloxy]-4'-methylacetophenon (Common name: Benzofenap), 2-[4-(2,4-Dichlorbenzoyl)-1,3-dimethyl-pyrazol-5-yloxy]-acetophenon (Common name: Pyrazoxyfen); b13) 3,5-Bis(methylthio-carbonyl)-2-difluormethyl-4-(2-methylpropyl)-6-trifluormethyl-pyridin (Common name: Dithiopyr); b15) 1-(4,6-Dimethoxypyrimidin-2-yl)-3-[1-methyl-4-(2-methyl-2H-tetrazol-5-yl)pyrazol-5-ylsulfonyl]-harnstoff (Common name: Azimsulfuron), ?-(4,6-Dimethoxypyrimidin-2-yl-carbamoyl-sulfamoyl)-Otoluolsäure-methylester (Common name: Bensulfuronmethyl), 1-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-3-[2-(2-methoxyethoxy)-phenylsulfonyl]-harnstoff (Common name: Cinosulfuron), 1-([2-(Cyclopropylcarbonyl)phenyl]aminosulfonyl}-3-(4,6-dimethoxypyrimidin-2-yl)-harnstoff (Common name: Cyclosulfamuron), N-(2-Chlorimidazo[1,2-a]-pyridin-3-yl-sulfonyl)-N'-(4,6-dimethoxy-2-pyrimidyl)-harnstoff (Common name: Imazosulfuron), 5-(4,6-Dimethoxypyrimidin-2-yl-carbamoylsulfamoyl)-1-methylpyrazol-4-carbonsäureethylester (Common name: Pyrazosulfuron-ethyl), b16) N -(1,2-Dimethylpropyl)-N -ethyl-6-methylthio-1,3,5-triazin-2,4-diamin (Common name: Dimethametryn), Bis(ethylamino)-6-methylthio-1,3,5-triazin (Common name: Simetryn, Simetryne); b19) (1RS,2SR,4SR)-1,4-Epoxy-p-menth-2-yl-2-methylbenzylether (Common name: Cinmethylin); b20) S-2-Methylpiperidinocarbonylmethyl-O,O-dipropylphosphorodithioat (Common name: Piperophos).

A herbicidal mixture, containing a) at least one cyclohexenone oxime ether of the formula I where the variables have the following meanings: and b) at least one of the following 44 herbicidal compounds from the groups b1) to b20) A herbicidal mixture as claimed in claim 1, containing as component b) at least one of the following 33 herbicides: b1) 2-bromo-3,3-dimethyl-N-(1-methyl-1-phenylethyl)-butyramide (common name: bromobutide), S-(1-methyl-1-phenylethyl) 1-piperidinecarbothioate (common name: dimepiperate), 4-ethoxybenz-2',3'-dihydrochloroanilide (common name: etobenzanid) and N-(3,4-dichlorophenyl)propanamide (common name: propanil); b2) 2-(1,3-benzothiazol-2-yloxy)-N-methylacetanilide, (common name: mefenacet); b3) (2,4-dichlorophenoxy)acetic acid (common name: 2,4-D), 4-(4-chloro-2-methylphenoxy)butanecarboxylic acid (common name: MCPB) and 2-(2-naphthyloxy)propionanilide (common name: naproanilide); b4) 3-isopropyl-lH-2,1,3-benzothiadiazin-4-(3H)one 2,2-dioxide (common name: bentazone); b5) 4-(2,4-dichlorobenzoyl)-1,3-dimethylpyrazol-5-yl-toluene-4-sulfonate (common name: pyrazolynate, pyrazolate) and 2-(2-chloro-4-mesylbenzoyl)-cyclohexane-1,3-dione (common name: sulcotrione); b6) S-benzyl 1,2-dimethylpropyl(ethyl)thiocarbamate (common name: esprocarb), N-(ethylthiocarbonyl)azepane (common name: molinate), 4-chlorobenzyl N,N-diethylthiocarbamate (common name: thiobencarb); b7) 3,7-dichloroquinoline-8-carboxylic acid (common name: quinclorac); b8) N-(butoxymethyl)-2-chloro-N-(2,6-diethylphenyl)-acetamide (common name: butachlor), (Z)-N-but-2-enyloxymethyl-2-chloro-2',6'-diethyl-acetanilide (common name: butenachlor), N-(2-propoxyethyl)-2-chloro-N-(2,6-diethylphenyl)-acetamide (common name: pretilachlor) and a-chloro-N-(3-methoxy-2-thienyl)methyl-2',6'-dimethylacetanilide (common name: thenylchlor); b11) ethyl 2-[4-(6-chlorobenzoxazol-2-yloxy)phenoxy]-propionate (common name: fenoxaprop-ethyl); b12) 2-[4-(2,4-dichloro-m-toluyl)-1,3-dimethyl-pyrazol-5-yloxy]-4'-methylacetophenone (common name: benzofenap) and 2-[4-(2,4-dichlorobenzoyl)-1,3-dimethylpyrazol-5-yloxy]acetophenone (common name: pyrazoxyfen); b13) 3,5-bis(methylthiocarbonyl)-2-difluoromethyl-4-(2-methylpropyl)-6-trifluoromethylpyridine (common name: dithiopyr); b15) 1-(4,6-dimethoxypyrimidin-2-yl)-3-[1-methyl-4-(2-methyl-2H-tetrazol-5-yl)pyrazol-5-ylsulfonyl]urea (common name: azimsulfuron), methyl ?-(4,6-dimethoxypyrimidin-2-ylcarbamoylsulfamoyl)-O-toluate (common name: bensulfuron-methyl), 1-(4,6-dimethoxy-1,3,5-triazin-2-yl)-3-[2-(2-methoxyethoxy)phenylsulfonyl]urea (common name: cino-sulfuron), 1-{[2-(cyclopropylcarbonyl)phenyl]aminosulfonyl}-3-(4,6-dimethoxypyrimidin-2-yl)urea (common name: cyclosulfamuron), N-(2-chloroimidazo[1,2-a]pyridin-3-ylsulfonyl)-N'-(4,6-dimethoxy-2-pyrimidyl)urea (common name: imazosulfuron) and ethyl 5-(4,6-dimethoxypyrimidin-2-ylcarbamoylsulfamoyl)-1-methylpyrazole-4-carboxylate (common name: pyrazosulfuron-ethyl); b16) N -(1,2-dimethylpropyl)-N -ethyl-6-methylthio-1,3,5-triazine-2,4-diamine (common name: dimethametryn)and bis(ethylamino)-6-methylthio-1,3,5-triazine (common name: simetryn, simetryne); b19) (1RS,2SR,4SR)-1,4-epoxy-p-menth-2-yl 2-methylbenzyl ether (common name: cinmethylin), and b20) S-2-methylpiperidinocarbonylmethyl O,O-dipropyl phosphorodithioate (common name: piperophos). A herbicidal composition containing at least one liquid and/or solid carrier, if desired at least one surface-active substance, and a) a herbicidally active amount of at least one cyclohexenone oxime ether of the formula I as claimed in claim 1 and b) a synergistically active amount of at least one herbicidal compound from group b) as claimed in claim 1 or 2.

Verbindung nach Anspruch 1, welche 2,3-Dihydro-N-[(4,6-dimethylpyrimidin-2-yl)aminocarbonyl]-2-(2-fluorethyl)-1,2-benzisothiazol-7-sulfonamid-1,1-dioxid ist.

The compound of Claim 1 which is 2,3-dihydro-N-[(4,6-dimethylpyrimidin-2-yl)aminocarbony]]-2-(2-fluoroethyl)-1,2-benzisothiazole-7-sulfonamide, 1,1-dioxide.

Verfahren zur Herstellung einer Zusammensetzung, die Nanopartikel umfaßt, die im wesentlichen aus folgendem bestehen: (a) einem kristallinen Antikrebsmittel, gewählt aus der Gruppe bestehend aus Chlormethin, Chlorambucil, Uramustin, Mannomustin, Mechlorethaninoxid, Cyclophosphamid, Ifosfamid, Trifosfamid, Tretamin, Thiotepa, Triazochon, Mitomycin, Busulfan, Carmustin, Lomustin, Semustin, Streptozotocin, alkylierenden Mitteln des Mitobronitol-, Decarbazin- und Procarbazintyps, Fluoruracil, Floxuridin, Tegafur, Cytarabin, Idoxuridin, Flucytosin, Mercaptopurin, Azathioprin, Tiamiprin, Vidarabin, Pentostatin, Puromycin, Vinblastin, Vincristin, Teniposid, Adriamycin, Daunomycin, Doctomycin, Mithramycin, Bleomycin, Mitomycin, L-Asparaginase, alpha-Interferon, Taxol, retinoischer Säure, Prednison, Hydroxyprogesteroncaproat, Medroxyprogesteronacetat, Megesterolacetat, Diethylstilbestrol, Testosteronpropionat, Fluoxomesteron, Flutamid, Leuprolid, 1,2,4-Benzotriazin-3-amin-1,4-dioxid, 1,2,4-Benzotriazin-7-amin-1,4-dioxid, Cisplatin, Carboplatin, Hydroxyharnstoff, Mitotan, Aminoglutethimid, Cyclosporin, Azathioprin, Sulfasalazion, Methoxsalen und Thalidomid; (b) einem Oberflächenwandler, der auf der Oberfläche des Antikrebsmittels adsorbiert ist, in einer Menge, die ausreichend ist, um eine mittlere Partikelgröße von weniger als 400nm zu erhalten; wobei die Nanopartikel mechanisch in einem flüssigen Dispersionsmedium erhalten werden, in dem das Antikrebsmittel eine Löslichkeit von weniger als 10mg/ml aufweist; wobei mindestens 90% der Partikel eine mittlere Partikelgröße von weniger als 400nm haben; und wobei der Oberflächenwandler mittels eines Screeningverfahrens so ausgewählt ist, daß er mit dem Antikrebsmittel kompatibel ist, so daß die Dispersion keine Ausflockung oder Partikelagglomeration zeigt, die mit bloßem Auge und insbesondere, wenn unter dem optischen Mikroskop bei 1000x mindestens zwei Tage nach der Herstellung beobachtet, sichtbar ist.

A process for obtaining a composition comprising nanoparticles consisting essentially of: (a) a crystalline anticancer agent selected from the group consisting of chlormethine, chlorambucile, uramustine, mannomustine, mechlorethaninoxide, cyclophosphamide, ifosfamide, trifosfamide, tretamine, thiotepa, triazoquone, mitomycine, busulfan, carmustine, lomustine, semustine, streptozotocine, alkylating agents of the mitobronitole, decarbazine and procarbazine type, fluorouracil, floxuridine, tegafur, cytarabine, idoxuridine, flucytosine, mercaptopurine, azathioprine, tiamiprine, vidarabine, pentostatin, puromycine, vinblastine, vincristine, teniposide, adriamycine, daunomycine, doctomycin, mithramycin, bleomycin, mitomycin, L-asparaginase, alpha-interferon, taxol, retinoic acid, prednisone, hydroxyprogesterone caproate, medroxyprogesterone acetate, megesterol acetate, diethylstilbestrol, testosterone propionate, fluoxomesterone, flutamide, leuprolide, 1,2,4-benzotriazin-3-amine 1,4-dioxide, 1,2,4-benzotriazine-7-amine 1,4-dioxide, cisplatin, carboplatin, hydroxyurea, mitotane, aminoglutethimide, cyclosporine, azathioprine, sulfasalazione, methoxsalen and thalidomide; (b) a surface modifier adsorbed on the surface of the anticancer agent, in an amount sufficient to maintain an average particle size of less than 400 nm; wherein the nanoparticles are mechanically obtained in a liquid dispersion medium in which the anticancer agent has a solubility of less than 10 mg/ml; at least 90% of the particles having an average particle size of less than 400 nm; and wherein the surface modifier is selected so as to be compatible with the anticancer agent through a screening process so that the dispersion exhibits no flocculation or particle agglomeration visible to the naked eye and particularly when viewed under the optical microscope at 1000x at least two days after preparation.