nuclease

nuclease

Nukleasen

nuclease

Nuklease

Nuclease

Nukleasen

revealing a possibly structurally related increase in resistance against nuclease degradation

enthüllt eine möglicherweise strukturell verwandten Zunahme des Widerstands gegen Nukleaseabbau

Nuclease digestion of chromosomes releases nucleosomes

Nucleaseverdau der Chromosomen Mitteilungen Nukleosomen

Biological analysis including bioburden & sterility, endotoxin, nuclease and protease tests

Biologische Analysen einschließlich Keimbelastung und Sterilität, Endotoxin, Nuclease und Protease-Tests

Examples which may be mentioned to illustrate but not restrict the term specific binding partner are: thyroxine-binding globulin, steroid-binding proteins, antibodies, antigens, haptens, enzymes, lectins, nucleic acids, repressors, oligonucleotides and polynucleotides, protein A, protein G, avidin, streptavidin, biotin, complement component Clq, nucleic acid-binding proteins, etc. Specific binding pairs are for example: antibody/antigen, antibody/hapten, operator/repressor, nuclease/nucleotide, biotin/avidin, lectin/polysaccharide, steroid/steroid-binding protein, active ingredient/active ingredient receptor, hormone/hormone receptor, enzyme/substrate, IgG/protein A, complementary oligonucleotides or polynucleotides, etc. [0024] It is now possible for the skilled worker, by providing the antibodies according to the invention, to identify, for example by competition experiments (see also Peters et al. (1985) Monoklonale Antikörper, Springer Verlag, section 12.2 “Epitop-Analyse”), other specific binding partners expressly including antibodies which bind to the epitope of an antibody according to the invention.

Zur Illustration des Begriffs spezifischer Bindungspartner, aber nicht als Einschränkung zu verstehend, sind z.B. zu nennen: Thyroxinbindendes Globulin, steroidbindende Proteine, Antikörper, Antigene, Haptene, Enzyme, Lektine, Nukleinsäuren, Repressoren, Oligo- und Polynukleotide, Protein A, Protein G, Avidin, Streptavidin, Biotin, Komplementkomponente C1q, nukleinsäurebindende Proteine, etc.. Spezifische Bindungspaare sind beispielsweise: Antikörper-Antigen, Antikörper-Hapten, Operator-Repressor, Nuclease-Nukleotid, Biotin-Avidin, Lektin-Polysaccharid, Steroid-steroidbindendes Protein, Wirkstoff-Wirkstoffrezeptor, Hormon-Hormonrezeptor, Enzym-Substrat, IgG-Protein A, komplementäre Oligooder Polynukleotide, etc.. Durch die Bereitstellung der erfindungsgemäßen Antikörper ist es dem Fachmann nun möglich, z.B. durch Kompetitionsexperimente (s.a.

The following may, for example, be mentioned in order to illustrate the term specific binding partner but without this being understood as a limitation: thyroxine-binding globulin, steroid-binding proteins, antibodies, antigens, haptens, enzymes, lectins, nucleic acids, repressors, oligonucleotides and polynucleotides, protein A, protein G, avidin, streptavidin, biotin, complement component Clq, nucleic acid-binding proteins, etc. Examples of specific binding pairs are: antibody-antigen, antibody-hapten, operator-repressor, nuclease-nucleotide, biotin-avidin, lectin-polysaccharide, steroid-steroid-binding protein, active compound-active compound receptor, hormone-hormone receptor, enzyme-substrate, IgG-protein A, complementary oligonucleotides or polynucleotides, etc. As a result of providing the antibodies according to the invention, it is now possible for the skilled person, for example by means of competition experiments (see also Peters et al. (1985) Monoklonale Antikörper [Monclonal Antibodies], Springer Verlag, Chapter 12.2 “Epitope analysis”], to identify other specific binding partners, with antibodies being expressly included, which bind to the epitope of an antibody according to the invention.

Zur Illustration des Begriffs spezifischer Bindungspartner, aber nicht als Einschränkung zu verstehend, sind z. B. zu nennen: thyroxinbindendes Globulin, steroidbindende Proteine, Antikörper, Antigene, Haptene, Enzyme, Lektine, Nukleinsäuren, Repressoren, Oligo- und Polynukleotide, Protein A, Protein G, Avidin, Streptavidin, Biotin, Komplementkomponente C1q, nukleinsäurebindende Proteine, etc. Spezifische Bindungspaare sind beispielsweise: Antikörper-Antigen, Antikörper-Hapten, Operator-Repressor, Nuclease-Nukleotid, Biotin-Avidin, Lektin-Polysaccharid, Steroid-steroidbindendes Protein, Wirkstoff-Wirkstoffrezeptor, Hormon-Hormonrezeptor, Enzym-Substrat, lgG-Protein A, komplementäre Oligo- oder Polynukleotide, etc. Durch die Bereitstellung der erfindungsgemäßen Antikörper ist es dem Fachmann nun möglich, z. B. durch Kompetitionsexperimente [s. a. Peters et al. (1985) Monoklonale Antikörper, Springer Verlag, Kapitel 12.2 "Epitop-Analyse], andere spezifische Bindungspartner, Antikörper ausdrücklich miteingeschlossen, zu identifizieren, die an das Epitop eines erfindungsgemäßen Antikörpers binden.